Vayne ADC is ranked S Tier and has a 54.02% win rate in LoL Patch 7.24. We've analyzed 2199 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of the Ruined King, Statikk Shiv, Infinity Edge, Phantom Dancer, and Rapid Firecannon. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Refillable Potion, and Warding Totem (Trinket). Vayne's Best ADC matchups include Kog'Maw, Ashe, and Jinx. Vayne's Best ADC counters are Miss Fortune and Draven.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Support Duo Queue Champions for Vayne ADC(49% - 51% win rate with Vayne)
Even ADC Matchups for Vayne ADC(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)
