Tier: Off MetaWin66.25%Role3.04%Pick0.13%Ban6.63%Games: 45KDA: 2.19Score: 52.07
Karthus Mid Lane is ranked Off Meta Tier and has a 66.25% win rate in LoL Patch 25.09. We've analyzed 45 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Blackfire Torch, Sorcerer's Shoes, Liandry's Torment, Shadowflame, Rabadon's Deathcap, and Zhonya's Hourglass. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Mel and Yasuo. Karthus's Best Mid Lane counters are Ahri.
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Karthus Summoner Spells


Win %
Pick %
63%
89%
56%
56%

65%
44%

40%
11%
Karthus Starting Items
Win %
Buy %


2

60%
89%


50%
4%
Karthus Runes
Win %
Pick %
57%
41%
79%
18%
67%
6%
52%
8%
Karthus Items

63%

55%

63%

61%

58%

71%

58%

25%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

58%
69%

65%
58%

100%
9%
Karthus Boots
Win %
Buy %

55%
89%
Karthus Situational Items
Win %
Buy %

75%
9%

38%
18%

100%
4%

33%
7%

33%
7%

0%
2%