Vayne ADC is ranked S Tier and has a 54.03% win rate in LoL Patch 7.24. We've analyzed 4007 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of the Ruined King, Statikk Shiv, Infinity Edge, Phantom Dancer, and Rapid Firecannon. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Boots of Speed, and Warding Totem (Trinket). Vayne's Best ADC matchups include Varus, Lucian, and Jhin. Vayne's Best ADC counters are Kog'Maw.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Support Duo Queue Champions for Vayne ADC(49% - 51% win rate with Vayne)
Best ADC Champions to Counter Vayne ADC(under 49% win rate for Vayne)
Even ADC Matchups for Vayne ADC(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)
