Tier: BWin44.91%Role19.74%Pick0.36%Ban0.50%Games: 241KDA: 2.23Score: 41.99
Karthus Mid Lane is ranked B Tier and has a 44.91% win rate in LoL Patch 10.25. We've analyzed 241 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Rabadon's Deathcap, and Morellonomicon. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Pantheon, Vel'Koz, and Cassiopeia. Karthus's Best Mid Lane counters are Sylas, Ahri, and Anivia.
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Karthus Summoner Spells


Win %
Pick %
50%
99%
45%
46%

59%
32%

43%
15%

57%
3%

50%
2%
Karthus Starting Items
Win %
Buy %


2

56%
52%


2

42%
34%
Karthus Runes
Win %
Pick %
55%
39%
46%
23%
59%
4%
57%
3%
Karthus Items

50%

52%

57%

52%

63%

55%

50%

49%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order
























Karthus Trinkets
Win %
Buy %

50%
95%

53%
26%

25%
7%
Karthus Boots
Win %
Buy %

52%
92%

75%
3%

25%
3%

50%
1%

0%
0%

0%
0%
Karthus Mythic Items
Win %
Buy %

50%
54%

52%
28%

50%
12%

25%
2%

0%
1%

0%
0%