Tier: Off MetaWin62.06%Role4.08%Pick0.88%Ban14.03%Games: 65KDA: 2.23Score: 52.32
Vayne Mid Lane is ranked Off Meta Tier and has a 62.06% win rate in LoL Patch 10.25. We've analyzed 65 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Guinsoo's Rageblade, Phantom Dancer, Mercurial Scimitar, and Guardian Angel. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Diana and Pantheon. Vayne's Best Mid Lane counters are Anivia.
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Vayne Summoner Spells


Win %
Pick %
52%
100%
55%
48%

64%
17%

40%
15%

60%
8%

20%
8%
Vayne Starting Items
Win %
Buy %



51%
78%



100%
3%
Vayne Runes
Win %
Pick %
49%
74%
88%
4%
100%
3%
50%
3%
Vayne Items

51%

50%

55%

58%

57%

100%

54%

100%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order


























Vayne Trinkets
Win %
Buy %

54%
91%

56%
69%

38%
12%
Vayne Boots
Win %
Buy %

51%
105%

100%
2%
Vayne Mythic Items
Win %
Buy %

55%
62%

56%
55%

52%
35%

67%
5%