Tier: SWin58.13%Role16.67%Pick0.56%Ban1.45%Games: 297KDA: 2.55Score: 54.96
Karthus Mid Lane is ranked S Tier and has a 58.13% win rate in LoL Patch 11.24. We've analyzed 297 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Veigar, Akali, and LeBlanc. Karthus's Best Mid Lane counters are Cassiopeia, Kayle, and Malzahar.
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Karthus Summoner Spells


Win %
Pick %
57%
99%
56%
54%

64%
34%

52%
8%

54%
4%

33%
1%
Karthus Starting Items
Win %
Buy %


2

62%
54%


2

53%
27%
Karthus Runes
Win %
Pick %
59%
38%
61%
17%
64%
8%
54%
4%
Karthus Items

57%

60%

59%

60%

63%

65%

58%

58%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order
























Karthus Trinkets
Win %
Buy %

58%
88%

57%
36%

59%
10%
Karthus Boots
Win %
Buy %

60%
88%

34%
12%

0%
0%
Karthus Mythic Items
Win %
Buy %

57%
86%

63%
6%

75%
4%

75%
1%

50%
1%

50%
1%