Tier: AWin45.67%Role15.75%Pick0.68%Ban2.54%Games: 115KDA: 2.20Score: 48.58
Karthus Mid Lane is ranked A Tier and has a 45.67% win rate in LoL Patch 11.24. We've analyzed 115 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Zhonya's Hourglass, Morellonomicon, Void Staff, and Rabadon's Deathcap. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Anivia, Corki, and Vladimir. Karthus's Best Mid Lane counters are Akshan, Irelia, and Zoe.
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Karthus Summoner Spells


Win %
Pick %
52%
90%
59%
61%

53%
30%

58%
17%

100%
2%

0%
1%
Karthus Starting Items
Win %
Buy %


2

55%
56%
Karthus Runes
Win %
Pick %
59%
28%
69%
25%
76%
10%
36%
18%
Karthus Items

55%

55%

61%

55%

62%

64%

59%

64%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

59%
93%

47%
46%

43%
6%
Karthus Boots
Win %
Buy %

55%
88%

63%
7%

0%
2%
Karthus Mythic Items
Win %
Buy %

55%
97%

60%
4%

100%
1%

0%
1%