Lissandra Mid Lane is ranked B Tier and has a 46.79% win rate in LoL Patch 8.24. We've analyzed 1033 Lissandra Mid Lane games to compile our statistical Lissandra Build Guide. For items, our build recommends: Sorcerer's Shoes, Hextech Protobelt-01, Luden's Echo, Zhonya's Hourglass, Morellonomicon, and Liandry's Torment. For runes, the strongest choice is Resolve (Primary) with Aftershock (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, Refillable Potion, and Warding Totem (Trinket). Lissandra's Best Mid Lane matchups include Xerath, Ziggs, and Aatrox. Lissandra's Best Mid Lane counters are Brand, Pyke, and Malzahar.
Lissandra Summoner Spells






Lissandra Starting Items





Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Trinkets



Lissandra Boots




