Tier: Off MetaWin44.80%Role6.74%Pick0.22%Ban3.73%Games: 301KDA: 1.95Score: 45.86
Karthus Mid Lane is ranked Off Meta Tier and has a 44.80% win rate in LoL Patch 11.24. We've analyzed 301 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Zhonya's Hourglass, Morellonomicon, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Vex, Azir, and Yasuo. Karthus's Best Mid Lane counters are Kassadin, Galio, and Irelia.
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Karthus Summoner Spells


Win %
Pick %
48%
95%
52%
56%

47%
40%

39%
6%

67%
1%

100%
0%
Karthus Starting Items
Win %
Buy %


2

52%
66%



60%
2%
Karthus Runes
Win %
Pick %
47%
34%
52%
24%
58%
13%
55%
3%
Karthus Items

51%

50%

53%

55%

50%

51%

48%

56%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

48%
87%

52%
51%

51%
16%
Karthus Boots
Win %
Buy %

50%
90%

36%
5%

100%
1%

0%
0%

0%
1%

0%
1%
Karthus Mythic Items
Win %
Buy %

51%
84%

88%
3%

50%
3%

20%
5%

14%
2%