Cassiopeia Mid Lane is ranked S Tier and has a 42.47% win rate in LoL Patch 8.24. We've analyzed 192 Cassiopeia Mid Lane games to compile our statistical Cassiopeia Build Guide. For items, our build recommends: Luden's Echo, Rylai's Crystal Scepter, Liandry's Torment, Zhonya's Hourglass, Morellonomicon, and Void Staff. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Cleanse. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, The Dark Seal, and Warding Totem (Trinket). Cassiopeia's Best Mid Lane matchups include Orianna, Ekko, and Ryze. Cassiopeia's Best Mid Lane counters are Irelia, Xerath, and Zed.
Cassiopeia Summoner Spells






Cassiopeia Starting Items





Cassiopeia Runes
Cassiopeia Items








Cassiopeia Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Cassiopeia Trinkets


