Tier: SWin56.42%Role79.43%Pick6.79%Ban6.48%Games: 280KDA: 2.42Score: 57.62
Vayne ADC is ranked S Tier and has a 56.42% win rate in LoL Patch 25.10. We've analyzed 280 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Guinsoo's Rageblade, Wit's End, Terminus, and Jak'Sho, The Protean. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Oracle Lens. Vayne's Best ADC matchups include Jhin, Ezreal, and Lucian. Vayne's Best ADC counters are Aphelios, Caitlyn, and Zeri.
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Vayne Summoner Spells


Win %
Pick %
58%
100%
56%
78%

73%
9%

59%
10%

50%
2%

67%
1%
Vayne Starting Items
Win %
Buy %



59%
90%



67%
2%
Vayne Runes
Win %
Pick %
60%
75%
36%
9%
65%
3%
94%
2%
Vayne Items

58%

58%

61%

60%

71%

66%

58%

42%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order





























Vayne Trinkets
Win %
Buy %

58%
74%

59%
65%

56%
6%
Vayne Boots
Win %
Buy %

58%
91%

68%
7%

50%
1%
Vayne Situational Items
Win %
Buy %

65%
19%

65%
8%

69%
6%

69%
6%

62%
5%

57%
5%