Tier: S+Win64.17%Role9.97%Pick0.34%Ban0.00%Games: 46KDA: 2.33Score: 57.19
Karthus Mid Lane is ranked S+ Tier and has a 64.17% win rate in LoL Swiftplay Patch 25.08. We've analyzed 46 Karthus Mid Lane games to compile our statistical Karthus Swiftplay Build Guide. For items, our build recommends: Blackfire Torch, Sorcerer's Shoes, Malignance, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Summon Aery (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Exhaust and Ignite. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Swiftplay Mid Lane matchups include Galio.
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Karthus Summoner Spells


Win %
Pick %
66%
83%
69%
63%

57%
30%

27%
24%
Karthus Starting Items
Win %
Buy %


2

67%
85%
Karthus Runes
Win %
Pick %
73%
42%
44%
30%
41%
11%
100%
2%
Karthus Items

57%

61%

57%

71%

58%

58%

71%

50%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

71%
46%

56%
59%

50%
4%
Karthus Boots
Win %
Buy %

61%
96%

50%
4%
Karthus Situational Items
Win %
Buy %

75%
17%

83%
13%

50%
17%

100%
7%

100%
2%

33%
7%