Karthus Support is ranked Off Meta Tier and has a 50.10% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 95 Karthus Support games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Zhonya's Hourglass, Shadowflame, Shard of True Ice, and Rabadon's Deathcap. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Spellthief's Edge, Health Potion, and Stealth Ward. Karthus's Best Spellbook Support matchups include Miss Fortune, Swain, and Xerath. Karthus's Best Spellbook Support counters are Pantheon.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Karthus Item Purchase Order
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30003600Karthus Ultimate Spellbook Stats
Karthus Trinkets
Karthus Boots
Karthus Mythic Items
Average ADC Duo Queue Champions for Karthus Support in Ultimate Spellbook(49% - 51% win rate with Karthus)
Best Support Champions to Counter Karthus Support(under 49% win rate for Karthus)
Even Support Matchups for Karthus Support in Ultimate Spellbook(49% - 51% win rate for Karthus)
Even ADC Matchups for Karthus Support in Ultimate Spellbook(49% - 51% win rate for Karthus)
