Seraphine Mid Lane is ranked B Tier and has a 35.34% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 91 Seraphine Mid Lane games to compile our statistical Seraphine Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Horizon Focus, Zhonya's Hourglass, Rylai's Crystal Scepter, and Seraph's Embrace. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Placeholder. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Seraphine's Best Spellbook Mid Lane matchups include Ekko, Veigar, and Viktor. Seraphine's Best Spellbook Mid Lane counters are LeBlanc and Yasuo.
Seraphine Summoner Spells





Seraphine Starting Items








Seraphine Runes
Seraphine Items








Seraphine Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Seraphine Item Purchase Order






















Seraphine Ultimate Spellbook Stats



























































Seraphine Trinkets



Seraphine Boots



Seraphine Mythic Items





