Kai'Sa Mid Lane is ranked B Tier and has a 42.33% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 92 Kai'Sa Mid Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Manamune, Berserker's Greaves, Nashor's Tooth, Crown of the Shattered Queen, The Collector, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Hail of Blades (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Placeholder. Starting items should include Tear of the Goddess, Long Sword, Refillable Potion, and Stealth Ward. Kai'Sa's Best Spellbook Mid Lane matchups include Zed and Yasuo. Kai'Sa's Best Spellbook Mid Lane counters are Fizz and Zoe.
Kai'Sa Summoner Spells




Kai'Sa Starting Items








Kai'Sa Runes
Kai'Sa Items








Kai'Sa Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Kai'Sa Item Purchase Order



























Kai'Sa Ultimate Spellbook Stats




























































Kai'Sa Trinkets



Kai'Sa Boots



Kai'Sa Mythic Items





