Karthus Support is ranked B Tier and has a 66.29% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 87 Karthus Support games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Shadowflame, Rabadon's Deathcap, Void Staff, and Shard of True Ice. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Spellthief's Edge, Health Potion, and Stealth Ward. Karthus's Best Spellbook Support matchups include Lulu, Lux, and Nami. Karthus's Best Spellbook Support counters are Nautilus, Seraphine, and Soraka.
Karthus Summoner Spells




Karthus Starting Items







Karthus Runes
Karthus Items








Karthus Skill Order
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Karthus Item Purchase Order


















Karthus Ultimate Spellbook Stats



























































Karthus Trinkets



Karthus Boots



Karthus Mythic Items



