Karthus Support is ranked Off Meta Tier and has a 58.50% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 61 Karthus Support games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Sorcerer's Shoes, Liandry's Anguish, Zhonya's Hourglass, Rabadon's Deathcap, Shadowflame, and Shard of True Ice. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Spellthief's Edge, Health Potion, and Stealth Ward. Karthus's Best Spellbook Support matchups include Blitzcrank, Lulu, and Seraphine. Karthus's Best Spellbook Support counters are Brand, Thresh, and Yuumi.
Karthus Summoner Spells





Karthus Starting Items








Karthus Runes
Karthus Items








Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order




















Karthus Ultimate Spellbook Stats



























































Karthus Trinkets



Karthus Boots


Karthus Mythic Items




