Vayne Mid Lane is ranked Off Meta Tier and has a 62.41% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 363 Vayne Mid Lane games to compile our statistical Vayne Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Immortal Shieldbow, Wit's End, Phantom Dancer, Blade of The Ruined King, and Bloodthirster. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Vampiric Scepter, Health Potion, and Stealth Ward. Vayne's Best Spellbook Mid Lane matchups include Akali, Kassadin, and Lissandra. Vayne's Best Spellbook Mid Lane counters are Yasuo, Renekton, and Swain.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
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R | R | R |