Seraphine Lane is ranked S+ Tier and has a 62.30% win rate in LoL Nexus Blitz Patch 10.25. We've analyzed 122 Seraphine Lane games to compile our statistical Seraphine Nexus Blitz Build Guide. For items, our build recommends: Luden's Tempest, Sorcerer's Shoes, Archangel's Staff, Rylai's Crystal Scepter, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Summon Aery (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Seraphine's Best Nexus Blitz Lane matchups include Yasuo, Vayne, and Anivia. Seraphine's Best Nexus Blitz Lane counters are Teemo, Diana, and Katarina.
Seraphine Summoner Spells






Seraphine Starting Items






Seraphine Runes
Seraphine Items








Seraphine Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Seraphine Item Purchase Order

























Seraphine Trinkets



Seraphine Boots




Seraphine Mythic Items




