Kai'Sa Top Lane is ranked Off Meta Tier and has a 44.09% win rate in LoL Patch 13.23. We've analyzed 5811 Kai'Sa Top Lane games to compile our statistical Kai'Sa Build Guide. For items, our build recommends: Manamune, Berserker's Greaves, Kraken Slayer, Luden's Tempest, Nashor's Tooth, and Rabadon's Deathcap. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Kai'Sa's Best Top Lane matchups include Akali, Volibear, and Kled. Kai'Sa's Best Top Lane counters are Yorick, Akshan, and Dr. Mundo.