Vayne ADC is ranked S Tier and has a 54.39% win rate in LoL Patch 7.24. We've analyzed 57 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Infinity Edge, Guinsoo's Rageblade, Rapid Firecannon, and Mercurial Scimitar. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Heal and Flash. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Long Sword, and Warding Totem (Trinket). Vayne's Best ADC matchups include Draven and Twitch. Vayne's Best ADC counters are Miss Fortune, Tristana, and Ezreal.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Below Average Support Duo Queue Champions for Vayne ADC(under 49% win rate with Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)
