Vayne ADC is ranked S Tier and has a 55.42% win rate in LoL Patch 7.24. We've analyzed 240 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Infinity Edge, Statikk Shiv, Blade of the Ruined King, Rapid Firecannon, and Phantom Dancer. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Long Sword, and Warding Totem (Trinket). Vayne's Best ADC matchups include Caitlyn, Varus, and Xayah. Vayne's Best ADC counters are Miss Fortune, Sivir, and Draven.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Support Duo Queue Champions for Vayne ADC(49% - 51% win rate with Vayne)
Even ADC Matchups for Vayne ADC(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)