Tier: DWin46.58%Role8.49%Pick0.16%Ban0.33%Games: 270KDA: 2.09Score: 47.56
Karthus Mid Lane is ranked D Tier and has a 46.58% win rate in LoL Patch 25.18. We've analyzed 270 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Blackfire Torch, Sorcerer's Shoes, Malignance, Shadowflame, Liandry's Torment, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Teleport and Flash. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Vladimir, Zed, and Lissandra. Karthus's Best Mid Lane counters are Malzahar, Ahri, and Anivia.
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Karthus Summoner Spells


Win %
Pick %
54%
59%
41%
70%

47%
41%

43%
23%

67%
2%

18%
4%
Karthus Starting Items
Win %
Buy %


2

47%
80%



100%
0%
Karthus Runes
Win %
Pick %
54%
28%
37%
38%
56%
15%
71%
2%
Karthus Items

49%

45%

45%

49%

36%

55%

47%

54%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

47%
87%

37%
18%

33%
4%
Karthus Boots
Win %
Buy %

45%
83%

33%
3%

100%
0%

0%
0%

0%
0%
Karthus Situational Items
Win %
Buy %

88%
10%

51%
16%

51%
14%

40%
15%

82%
4%

88%
3%