Vayne ADC is ranked A Tier and has a 53.69% win rate in LoL Patch 7.24. We've analyzed 149 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Infinity Edge, Statikk Shiv, Phantom Dancer, Rapid Firecannon, and Mercurial Scimitar. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Refillable Potion, and Warding Totem (Trinket). Vayne's Best ADC matchups include Jhin, Lucian, and Miss Fortune. Vayne's Best ADC counters are Varus, Kalista, and Ezreal.
Vayne Summoner Spells



Vayne Starting Items





Vayne Runes
Vayne Items








Vayne Skill Order
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![]() | R | R | R |
Vayne Trinkets



Vayne Boots


