Vayne ADC is ranked A Tier and has a 55.93% win rate in LoL Patch 7.24. We've analyzed 472 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Infinity Edge, Phantom Dancer, Rapid Firecannon, and Mercurial Scimitar. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Boots of Speed, and Warding Totem (Trinket). Vayne's Best ADC matchups include Ashe, Sivir, and Twitch. Vayne's Best ADC counters are Draven and Lucian.
Vayne Summoner Spells



Vayne Starting Items





Vayne Runes
Vayne Items








Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Trinkets




Vayne Boots


