Cassiopeia Mid Lane is ranked S Tier and has a 51.82% win rate in LoL Patch 8.24. We've analyzed 577 Cassiopeia Mid Lane games to compile our statistical Cassiopeia Build Guide. For items, our build recommends: Luden's Echo, Rylai's Crystal Scepter, Mejai's Soulstealer, Liandry's Torment, Zhonya's Hourglass, and Morellonomicon. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, The Dark Seal, and Warding Totem (Trinket). Cassiopeia's Best Mid Lane matchups include Vel'Koz, Aatrox, and Brand. Cassiopeia's Best Mid Lane counters are Neeko, Anivia, and Sion.
Cassiopeia Summoner Spells






Cassiopeia Starting Items





Cassiopeia Runes
Cassiopeia Items








Cassiopeia Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Cassiopeia Trinkets


