Tier: Off MetaWin54.55%Role1.43%Pick0.07%Ban3.24%Games: 22KDA: 1.26Score: 50.46
Vayne Mid Lane is ranked Off Meta Tier and has a 54.55% win rate in LoL Patch 25.09. We've analyzed 22 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Guinsoo's Rageblade, Wit's End, Trinity Force, and Terminus. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Galio.
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Vayne Summoner Spells


Win %
Pick %
55%
100%
80%
23%

50%
18%

67%
14%

29%
32%

100%
5%
Vayne Starting Items
Win %
Buy %



56%
82%



0%
5%
Vayne Runes
Win %
Pick %
47%
66%
100%
14%
100%
5%
0%
5%
Vayne Items

67%

65%

67%

75%

67%

67%

47%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order





























Vayne Trinkets
Win %
Buy %

47%
77%

63%
36%

50%
9%
Vayne Boots
Win %
Buy %

67%
95%

0%
5%

0%
5%
Vayne Situational Items
Win %
Buy %

67%
14%

50%
9%

50%
9%

50%
9%

100%
5%

100%
5%