Karthus Mid Lane is ranked B Tier and has a 55.56% win rate in LoL Patch 7.24. We've analyzed 45 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Void Staff, Zhonya's Hourglass, Rabadon's Deathcap, and Liandry's Torment. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and <pathBonus><pathSorcery>Sorcery</pathSorcery> + <pathPrecision>Precision</pathPrecision> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Health Potion, Doran's Ring, Boots of Speed, Control Ward, and Warding Totem (Trinket). Karthus's Best Mid Lane matchups include Azir and Kassadin.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Karthus Trinkets
Karthus Boots
Best Jungle Duo Queue Champions for Karthus Mid Lane(over 51% win rate with Karthus)
Average Jungle Duo Queue Champions for Karthus Mid Lane(49% - 51% win rate with Karthus)
Even Mid Lane Matchups for Karthus Mid Lane(49% - 51% win rate for Karthus)
