Tier: Off MetaWin58.33%Role4.85%Pick0.20%Ban8.40%Games: 10KDA: 1.65Score: 51.41
Vayne Mid Lane is ranked Off Meta Tier and has a 58.33% win rate in LoL Patch 25.09. We've analyzed 10 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Kraken Slayer, Trinity Force, Blade of The Ruined King, Yun Tal Wildarrows, and Guinsoo's Rageblade. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Fizz.
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Vayne Summoner Spells


Win %
Pick %
50%
100%
43%
70%

50%
20%

100%
10%
Vayne Starting Items
Win %
Buy %



60%
50%


2
50%
40%
Vayne Runes
Win %
Pick %
64%
23%
38%
53%
100%
10%
Vayne Items

60%

17%

100%

80%

67%

100%

44%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order





























Vayne Trinkets
Win %
Buy %

44%
90%

67%
30%

100%
10%
Vayne Boots
Win %
Buy %

60%
50%

67%
30%

50%
20%

0%
10%
Vayne Situational Items
Win %
Buy %

100%
10%

100%
10%

50%
20%

0%
10%

0%
20%