Lissandra Mid Lane is ranked B Tier and has a 55.00% win rate in LoL Patch 7.24. We've analyzed 20 Lissandra Mid Lane games to compile our statistical Lissandra Build Guide. For items, our build recommends: Hextech Protobelt-01, Rod of Ages, Ionian Boots of Lucidity, Morellonomicon, Zhonya's Hourglass, and Liandry's Torment. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and <pathBonus><pathSorcery>Sorcery</pathSorcery> + <pathInspiration>Inspiration</pathInspiration> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, and Warding Totem (Trinket). Lissandra's Best Mid Lane matchups include Corki.
Lissandra Summoner Spells



Lissandra Starting Items




Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Trinkets


Lissandra Boots


