Vayne ADC is ranked S Tier and has a 58.00% win rate in LoL Patch 7.24. We've analyzed 100 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Infinity Edge, Phantom Dancer, Rapid Firecannon, and The Bloodthirster. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Refillable Potion, and Warding Totem (Trinket). Vayne's Best ADC matchups include Lucian, Tristana, and Jhin. Vayne's Best ADC counters are Varus, Xayah, and Kalista.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Support Duo Queue Champions for Vayne ADC(49% - 51% win rate with Vayne)
Below Average Support Duo Queue Champions for Vayne ADC(under 49% win rate with Vayne)
Even ADC Matchups for Vayne ADC(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)
