Tier: BWin54.79%Role46.79%Pick3.09%Ban17.88%Games: 73KDA: 2.44Score: 53.20
Karthus Mid Lane is ranked B Tier and has a 54.79% win rate in LoL Patch 8.24. We've analyzed 73 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Morellonomicon, Zhonya's Hourglass, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Smite. Starting items should include Health Potion, Doran's Ring, Hunter's Talisman, Refillable Potion, and Warding Totem (Trinket). Karthus's Best Mid Lane matchups include Ahri and Kassadin. Karthus's Best Mid Lane counters are Cassiopeia, Orianna, and Twisted Fate.
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Karthus Summoner Spells


Win %
Pick %
55%
100%
56%
34%

58%
26%

45%
27%

86%
10%

0%
3%
Karthus Starting Items

62%

58%

50%

41%

54%
Karthus Runes
Win %
Pick %
61%
67%
49%
8%
46%
3%
100%
1%
Karthus Items

48%

54%

55%

52%

73%

61%

56%

50%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Trinkets
Win %
Buy %

56%
99%

63%
41%

80%
7%
Karthus Boots
Win %
Buy %

54%
104%

0%
1%

0%
1%