Lissandra Mid Lane is ranked C Tier and has a 27.18% win rate in LoL One For All Patch 14.8. We've analyzed 313 Lissandra Mid Lane games to compile our statistical Lissandra OFA Build Guide. For items, our build recommends: Malignance, Sorcerer's Shoes, Stormsurge, Shadowflame, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Amplifying Tome, Sapphire Crystal, Health Potion, and Stealth Ward. Lissandra's Best OFA Mid Lane matchups include Blitzcrank, Aphelios, and Heimerdinger. Lissandra's Best OFA Mid Lane counters are Kai'Sa, Akshan, and Cho'Gath.
Lissandra Summoner Spells






Lissandra Starting Items







Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order






















Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





