Tier: SWin54.16%Role72.15%Pick3.78%Ban8.64%Games: 2199KDA: 2.45Score: 52.50
Karthus Mid Lane is ranked S Tier and has a 54.16% win rate in LoL Patch 8.24. We've analyzed 2199 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Luden's Echo, Morellonomicon, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, The Dark Seal, Refillable Potion, and Warding Totem (Trinket). Karthus's Best Mid Lane matchups include Riven, Pyke, and Akali. Karthus's Best Mid Lane counters are Cassiopeia, Ziggs, and Gragas.
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Karthus Summoner Spells


Win %
Pick %
54%
97%
55%
35%

53%
28%

57%
18%

52%
11%

48%
7%
Karthus Starting Items

54%

55%

54%

53%

54%
Karthus Runes
Win %
Pick %
56%
46%
51%
11%
56%
7%
48%
9%
Karthus Items

53%

55%

58%

55%

53%

59%

54%

57%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Trinkets
Win %
Buy %

54%
92%

53%
13%

63%
3%
Karthus Boots
Win %
Buy %

55%
89%

48%
4%

50%
1%

43%
0%

100%
0%

25%
0%