Lissandra Mid Lane is ranked S Tier and has a 52.91% win rate in LoL Swiftplay Patch 25.15. We've analyzed 1693 Lissandra Mid Lane games to compile our statistical Lissandra Swiftplay Build Guide. For items, our build recommends: Luden's Companion, Sorcerer's Shoes, Malignance, Zhonya's Hourglass, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Lissandra's Best Swiftplay Mid Lane matchups include Syndra, Corki, and Heimerdinger. Lissandra's Best Swiftplay Mid Lane counters are Jayce, Neeko, and Zilean.
Lissandra Summoner Spells






Lissandra Starting Items






Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order


























Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





