Lissandra Mid Lane is ranked A Tier and has a 51.08% win rate in LoL Patch 13.23. We've analyzed 132951 Lissandra Mid Lane games to compile our statistical Lissandra Build Guide. For items, our build recommends: Sorcerer's Shoes, Luden's Tempest, Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Lissandra's Best Mid Lane matchups include Yasuo, Azir, and LeBlanc. Lissandra's Best Mid Lane counters are Kayle, Zilean, and Quinn.