Zoe Mid Lane is ranked A Tier and has a 51.92% win rate in LoL Patch 13.24. We've analyzed 25920 Zoe Mid Lane games to compile our statistical Zoe Build Guide. For items, our build recommends: Sorcerer's Shoes, Luden's Tempest, Shadowflame, Horizon Focus, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Zoe's Best Mid Lane matchups include Hwei, Corki, and Sion. Zoe's Best Mid Lane counters are Gangplank, Cassiopeia, and Swain.