Cassiopeia Mid Lane is ranked S Tier and has a 65.52% win rate in LoL Patch 9.24. We've analyzed 87 Cassiopeia Mid Lane games to compile our statistical Cassiopeia Build Guide. For items, our build recommends: Rylai's Crystal Scepter, Zhonya's Hourglass, Liandry's Torment, Morellonomicon, Rabadon's Deathcap, and Seraph's Embrace. For runes, the strongest choice is Precision (Primary) with Conqueror (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, Refillable Potion, and Warding Totem (Trinket). Cassiopeia's Best Mid Lane matchups include Syndra, Irelia, and Kassadin. Cassiopeia's Best Mid Lane counters are LeBlanc and Zed.
Cassiopeia Summoner Spells






Cassiopeia Starting Items





Cassiopeia Runes
Cassiopeia Items








Cassiopeia Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Cassiopeia Trinkets


