Tier: Off MetaWin51.50%Role8.23%Pick0.12%Ban0.35%Games: 348KDA: 2.30Score: 52.04
Karthus Mid Lane is ranked Off Meta Tier and has a 51.50% win rate in LoL Patch 25.12. We've analyzed 348 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Malignance, Blackfire Torch, Sorcerer's Shoes, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Exhaust and Flash. Starting items should include Doran's Ring, Health Potion, and Oracle Lens. Karthus's Best Mid Lane matchups include Sylas, LeBlanc, and Twisted Fate. Karthus's Best Mid Lane counters are Zoe, Aurelion Sol, and Aurora.
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Karthus Summoner Spells


Win %
Pick %
54%
66%
48%
52%

50%
45%

48%
30%

36%
4%

29%
2%
Karthus Starting Items
Win %
Buy %


2

50%
75%


50%
1%
Karthus Runes
Win %
Pick %
51%
63%
47%
22%
51%
8%
100%
0%
Karthus Items

51%

56%

53%

53%

54%

64%

49%

57%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

49%
93%

54%
16%

57%
4%
Karthus Boots
Win %
Buy %

53%
78%

60%
6%

100%
0%

0%
1%

0%
0%
Karthus Situational Items
Win %
Buy %

52%
20%

51%
16%

60%
10%

52%
8%

90%
3%

39%
5%