Tier: CWin49.58%Role21.31%Pick0.30%Ban0.31%Games: 2231KDA: 2.41Score: 51.27
Karthus Mid Lane is ranked C Tier and has a 49.58% win rate in LoL Patch 13.1. We've analyzed 2231 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Gragas, Vel'Koz, and Cassiopeia. Karthus's Best Mid Lane counters are Anivia, Brand, and Rumble.
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Karthus Summoner Spells


Win %
Pick %
49%
97%
46%
52%

50%
29%

55%
14%

51%
4%

46%
2%
Karthus Starting Items
Win %
Buy %


2

50%
51%


2

45%
26%
Karthus Runes
Win %
Pick %
53%
43%
45%
14%
49%
11%
42%
2%
Karthus Items

52%

51%

51%

52%

52%

56%

49%

60%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

49%
87%

51%
32%

50%
11%
Karthus Boots
Win %
Buy %

51%
84%

46%
7%

50%
1%

67%
1%

57%
0%

33%
0%
Karthus Mythic Items
Win %
Buy %

52%
66%

45%
18%

46%
7%

35%
4%

47%
1%

80%
0%