Tier: Off MetaWin62.00%Role1.83%Pick0.11%Ban3.60%Games: 234KDA: 2.34Score: 58.02
Vayne Mid Lane is ranked Off Meta Tier and has a 62.00% win rate in LoL Patch 25.10. We've analyzed 234 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Wit's End, and Bloodthirster. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Ahri, Aurelion Sol, and Aurora. Vayne's Best Mid Lane counters are Hwei, Irelia, and Malzahar.
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Vayne Summoner Spells


Win %
Pick %
56%
99%
52%
38%

67%
18%

68%
16%

53%
8%

30%
12%
Vayne Starting Items
Win %
Buy %



58%
83%



57%
6%
Vayne Runes
Win %
Pick %
59%
26%
52%
36%
66%
8%
100%
1%
Vayne Items

56%

57%

62%

57%

52%

70%

54%

48%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order




























Vayne Trinkets
Win %
Buy %

54%
92%

57%
32%

50%
12%
Vayne Boots
Win %
Buy %

56%
82%

54%
15%

75%
2%

25%
2%

17%
3%
Vayne Situational Items
Win %
Buy %

78%
10%

52%
13%

64%
11%

54%
11%

54%
11%

59%
9%