Vayne ADC is ranked S+ Tier and has a 53.04% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 2240 Vayne ADC games to compile our statistical Vayne Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Immortal Shieldbow, Phantom Dancer, Blade of The Ruined King, Wit's End, and Mortal Reminder. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Vayne's Best Spellbook ADC matchups include Varus, Twisted Fate, and Senna. Vayne's Best Spellbook ADC counters are Veigar, Malzahar, and Syndra.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Item Purchase Order
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2500Vayne Ultimate Spellbook Stats
Vayne Trinkets
Vayne Boots
Vayne Mythic Items
Average Support Duo Queue Champions for Vayne ADC in Ultimate Spellbook(49% - 51% win rate with Vayne)
Even ADC Matchups for Vayne ADC in Ultimate Spellbook(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC in Ultimate Spellbook(49% - 51% win rate for Vayne)
