Seraphine Mid Lane is ranked A Tier and has a 49.01% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 824 Seraphine Mid Lane games to compile our statistical Seraphine Spellbook Build Guide. For items, our build recommends: Luden's Companion, Sorcerer's Shoes, Archangel's Staff, Liandry's Torment, Rylai's Crystal Scepter, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Seraphine's Best Spellbook Mid Lane matchups include Vladimir, Vel'Koz, and Xerath. Seraphine's Best Spellbook Mid Lane counters are Aurelion Sol, Lissandra, and Cho'Gath.
Seraphine Summoner Spells






Seraphine Starting Items








Seraphine Runes
Seraphine Items








Seraphine Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | R | R | R |
Seraphine Item Purchase Order
























Seraphine Ultimate Spellbook Stats
























































































Seraphine Trinkets



Seraphine Boots






Seraphine Situational Items





