Tier: CWin48.48%Role23.91%Pick0.68%Games: 33KDA: 2.18Score: 48.59
Karthus ADC is ranked C Tier and has a 48.48% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 33 Karthus ADC games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Zhonya's Hourglass, Shadowflame, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Spellbook ADC matchups include Kai'Sa. Karthus's Best Spellbook ADC counters are Vayne.
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Karthus Summoner Spells


Win %
Pick %
48%
100%
44%
82%

60%
15%

100%
3%
Karthus Starting Items
Win %
Buy %



2

56%
27%



0%
6%
Karthus Runes
Win %
Pick %
57%
67%
38%
13%
0%
3%
0%
3%
Karthus Items

47%

44%

56%

53%

48%

55%

43%

36%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order
























Karthus Ultimate Spellbook Stats

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Karthus Trinkets
Win %
Buy %

43%
70%

50%
36%

75%
12%
Karthus Boots
Win %
Buy %

44%
97%

60%
15%
Karthus Mythic Items
Win %
Buy %

47%
91%

50%
12%