Kai'Sa Mid Lane is ranked Off Meta Tier and has a 48.38% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 904 Kai'Sa Mid Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Manamune, Berserker's Greaves, Luden's Tempest, Nashor's Tooth, The Collector, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Hail of Blades (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Kai'Sa's Best Spellbook Mid Lane matchups include Seraphine, Anivia, and Aurelion Sol. Kai'Sa's Best Spellbook Mid Lane counters are Heimerdinger, Twisted Fate, and Yone.
Kai'Sa Summoner Spells






Kai'Sa Starting Items








Kai'Sa Runes
Kai'Sa Items








Kai'Sa Skill Order
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Kai'Sa Item Purchase Order



























Kai'Sa Ultimate Spellbook Stats




























































Kai'Sa Trinkets



Kai'Sa Boots






Kai'Sa Mythic Items





