Karthus Support is ranked D Tier and has a 60.75% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 228 Karthus Support games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Demonic Embrace, Shadowflame, Rabadon's Deathcap, and Shard of True Ice. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Spellthief's Edge, Health Potion, and Stealth Ward. Karthus's Best Spellbook Support matchups include Karma, Lissandra, and Sona. Karthus's Best Spellbook Support counters are Morgana, Lux, and Shaco.
Karthus Summoner Spells






Karthus Starting Items








Karthus Runes
Karthus Items








Karthus Skill Order
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Karthus Item Purchase Order




















Karthus Ultimate Spellbook Stats



























































Karthus Trinkets



Karthus Boots





Karthus Mythic Items




