Tier: SWin54.91%Role69.25%Pick5.84%Games: 762KDA: 1.98Score: 56.67
Vayne ADC is ranked S Tier and has a 54.91% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 762 Vayne ADC games to compile our statistical Vayne Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Terminus, and Wit's End. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Vayne's Best Spellbook ADC matchups include Smolder, Veigar, and Twitch. Vayne's Best Spellbook ADC counters are Pantheon, Vel'Koz, and Malzahar.
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Vayne Summoner Spells


Win %
Pick %
55%
99%
55%
96%

50%
3%

60%
1%

50%
0%

100%
0%
Vayne Starting Items
Win %
Buy %



3

57%
19%



69%
7%
Vayne Runes
Win %
Pick %
55%
64%
53%
21%
52%
2%
45%
1%
Vayne Items

55%

55%

58%

58%

54%

59%

56%

55%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order



























Vayne Ultimate Spellbook Stats

12%

3%

2%

3%

8%

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Vayne Trinkets
Win %
Buy %

56%
89%

57%
25%

67%
5%
Vayne Boots
Win %
Buy %

55%
91%

57%
19%

54%
7%

46%
4%

46%
2%

100%
0%
Vayne Situational Items
Win %
Buy %

60%
19%

59%
16%

54%
16%

55%
15%

49%
16%

58%
11%