Tier: SWin56.94%Role33.03%Pick0.78%Ban1.15%Games: 72KDA: 2.81Score: 56.38
Karthus Lane is ranked S Tier and has a 56.94% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 72 Karthus Lane games to compile our statistical Karthus Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Shadowflame, Cosmic Drive, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Nexus Blitz Lane matchups include Ashe, Garen, and Mordekaiser. Karthus's Best Nexus Blitz Lane counters are Kai'Sa, Malzahar, and Senna.
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Karthus Summoner Spells


Win %
Pick %
58%
99%
59%
64%

80%
7%

50%
11%

50%
8%

38%
11%
Karthus Starting Items
Win %
Buy %


2

57%
51%


2

55%
28%
Karthus Runes
Win %
Pick %
65%
44%
48%
43%
59%
7%
100%
1%
Karthus Items

61%

52%

68%

55%

58%

59%

57%

43%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order
























Karthus Trinkets
Win %
Buy %

57%
100%

100%
1%
Karthus Boots
Win %
Buy %

52%
64%

50%
25%
Karthus Mythic Items
Win %
Buy %

61%
71%

44%
22%

0%
1%