Cassiopeia Support is ranked Off Meta Tier and has a 41.77% win rate in LoL Patch 13.23. We've analyzed 1245 Cassiopeia Support games to compile our statistical Cassiopeia Build Guide. For items, our build recommends: Liandry's Anguish, Rylai's Crystal Scepter, Archangel's Staff, Zhonya's Hourglass, Shard of True Ice, and Demonic Embrace. For runes, the strongest choice is Precision (Primary) with Conqueror (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Spellthief's Edge, Health Potion, and Stealth Ward. Cassiopeia's Best Support matchups include Shaco, Teemo, and Milio. Cassiopeia's Best Support counters are Xerath, Karma, and Neeko.