Vayne Mid Lane is ranked Off Meta Tier and has a 36.00% win rate in LoL Patch 7.24. We've analyzed 25 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Infinity Edge, Rapid Firecannon, Blade of the Ruined King, and Guardian Angel. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Health Potion, Doran's Blade, Dagger, Long Sword, and Warding Totem (Trinket). Vayne's Best Mid Lane matchups include Lux. Vayne's Best Mid Lane counters are Diana, Xerath, and Yasuo.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Jungle Duo Queue Champions for Vayne Mid Lane(49% - 51% win rate with Vayne)
Best Mid Lane Matchups for Vayne Mid Lane(over 51% win rate for Vayne)
Even Mid Lane Matchups for Vayne Mid Lane(49% - 51% win rate for Vayne)
